| 2022-09-29 19:00:26September 29, 2022 | Football: Ireton vs. John Paul the Great | 29 - 0 | WCAC Lower Division | Saint John Paul the Great Catholic High School |
| 2022-09-30 07:48:11September 30, 2022 | Football: Edmondson-Westside vs. Bullis | 0 - 31 | IAC Football | Bullis School |
| 2022-09-30 16:30:00September 30, 2022 | Football: Collegiate vs. Episcopal | 16 - 10 | IAC Football | Episcopal High School |
| 2022-09-30 18:00:08September 30, 2022 | Football: Dunbar vs. Eastern | 52 - 0 | Stars Division, Stripes Division | Eastern High School |
| 2022-09-30 18:00:08September 30, 2022 | Football: Phelps vs. Ron Brown | 0 - 21 | Stripes Division | Ron Brown High School |
| 2022-09-30 18:00:25September 30, 2022 | Football: Bell vs. Coolidge | 14 - 15 | Stripes Division | Coolidge High School |
| 2022-09-30 18:00:30September 30, 2022 | Football: Cardozo vs. Anandale | 8 - 57 | Stripes Division | Cardozo Education Campus |
| 2022-09-30 18:00:39September 30, 2022 | Football: Roosevelt vs. Jackson-Reed | 45 - 3 | Stars Division | Jackson Reed High School |
| 2022-09-30 18:00:48September 30, 2022 | Football: Ballou vs. H.D. Woodson | 6 - 18 | Stars Division | H.D. Woodson High School |
| 2022-09-30 18:00:52September 30, 2022 | Football: McKinley vs. Anacostia | 6 - 16 | Stripes Division | Anacostia High School |
| 2022-09-30 19:00:04September 30, 2022 | Football: St. Albans vs. Paul VI | 6 - 23 | IAC Football, WCAC Lower Division | Paul VI High School |
| 2022-09-30 19:00:16September 30, 2022 | Football: Gonzaga vs. Friendship Collegiate | 34 - 7 | WCAC Upper Division | Friendship Collegiate |
| 2022-09-30 19:00:42September 30, 2022 | Football: Riverdale Baptist vs. Georgetown Prep | 0 - 35 | IAC Football | Georgetown Preparatory School |
| 2022-09-30 19:00:48September 30, 2022 | Football: Life Christian Academy vs. Good Counsel | 7 - 36 | WCAC Upper Division | Good Counsel High School |
| 2022-09-30 19:00:58September 30, 2022 | Football: St. Mary's Ryken vs. Trinity Episcopal | 16 - 20 | WCAC Lower Division | Trinity Episcopal School |
| 2022-10-01 12:00:39October 1, 2022 | Football: O'Connell vs. St. Michael the Archangel | 7 - 35 | WCAC Lower Division | Saint Michael the Archangel Catholic High School |
| 2022-10-01 14:00:04October 1, 2022 | Football: Cedar Grove (GA) vs. St. John's | 35 - 13 | WCAC Upper Division | St. John's College High School |
| 2022-10-01 14:00:23October 1, 2022 | Football: McNamara vs. Carroll | 12 - 22 | WCAC Lower Division, WCAC Upper Division | Archbishop Carroll High School |
| 2022-10-01 14:00:33October 1, 2022 | Football: Northumberland vs. St. Stephen's & St. Agnes | 14:00:33Canceled | IAC Football | St. Stephen's & St. Agnes School |
| 2022-10-01 14:30:54October 1, 2022 | Football: Landon vs. Haverford School | 7 - 44 | IAC Football | Haverford School |
