| 2021-08-28 14:00:09August 28, 2021 | Football: Don Bosco (NJ) @ St. John's | 6 - 27 | St. John's College High School |
| 2021-09-04 14:00:29September 4, 2021 | Football: Butler (NC) @ St. John's | 0 - 33 | St. John's College High School |
| 2021-09-11 14:00:57September 11, 2021 | Football: St. John's vs. Cardinal Hayes | 7 - 38 | St. John's College High School |
| 2021-09-18 14:00:41September 18, 2021 | Football: Life Christian Academy (VA) @ St. John's | 0 - 31 | St. John's College High School |
| 2021-09-25 13:00:39September 25, 2021 | Football: St. John's @ Archbishop Wood (PA) | 38 - 0 | Archbishop Wood High School |
| 2021-10-09 14:00:20October 9, 2021 | Football: McNamara @ St. John's | 0 - 35 | St. John's College High School |
| 2021-10-22 19:00:07October 22, 2021 | Football: St. John's @ DeMatha | 14 - 7 | DeMatha High School |
| 2021-10-30 13:00:58October 30, 2021 | Football: Good Counsel @ St. John's | 21 - 34 | St. John's College High School |
| 2021-11-05 18:30:32November 5, 2021 | Football: St. John's @ Gonzaga | 20 - 17 | Gonzaga College High School |
| 2021-11-14 13:00:00November 14, 2021 | Football: WCAC Playoffs: Gonzaga vs. St. John's | 0 - 28 | St. John's College High School |
| 2021-11-21 18:00:08November 21, 2021 | WCAC Football: 2021 Capital League Championship: Good Counsel vs. St. John’s | 14 - 30 | PG Sports & Learning Complex |
